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Write a review about how a mutation in SOD1 gene can affect the protein structure, maturation and conformation. Later, explain how those changes can be related to Amyotrophic Lateral Sclerosis. Instructions: Times new roman, 12 Single space Style: APA. Make sure to include the doi link in the references. Use primary references (research articles, review articles, etc.) Number of pages with information: 6

You are invited to participate in a Part-time work and study offer for current staff or students. It is an opportunity to earn up to $350 weekly. The job is exciting, flexible and will not affect your current job or studies. Don't miss this kindly send a DM so that i can give you necessary information

We have pre-made labels that are saved as PNG files, and group into folders by categories. Our desire is for user to just click on specific image and then it would automatically print 1 copy to the connected default printer, instead of opening up the ...into folders by categories. Our desire is for user to just click on specific image and then it would automatically print 1 copy to the connected default printer, instead of opening up the image in another window or a print dialog box. The computer screen is a touch enabled 23" screen with 1920x1080 resolution, so sizing of navigation and image tiles should be appropriate for touch and not mouse cursor. We want to specify the starting directory, for instance C:label. A clean simple black background is desired. More details avail...

I have been task...level of detail. The surface geometry itself must be kept relatively simple, with few holes and intersections, so I can modify it easily for 3D printing and to add features to the internal structure. These will include things like attachment points for an internal PVC pipe skeleton, places to attach lights and/or laser diodes to the eye sockets, and other internal structure pieces that shouldn't affect the surface. There are relatively few images of this character. The attached image is all available concept art and screens from the movie. There are some differences between the concept images and the movie screenshots. Please note that the tail is actually modeled in a very similar way to the legs in the movie, and not simply a tuft of hair as it is in the ...

Hello, our need is to have unified in real time a development done in Unreal Engine, with IBM Watson Assistant, so that if something is updated in the latter, immediately affect the visual interface developed in Unreal.

...should also have clearly moving objects within it or the rotoscoping effect will not be very apparent or interesting. Learning Objectives have the ability to create a video composition using multiple still frames that are hand drawn have the ability to create a video composition that creates a consistent artistic direction, aesthetic and mood have an understanding of how variable frame rates affect the overall speed and aesthetic have the ability to output (render) a final video composition to a shareable format Project Parameters final animation must be at least 20 sec/200 frames long The final video should be silent the final video must be in full HD 1920x1080 at 24 fps final project file must be submitted as an MP4 file using the H.264 codec Hi guys, This is my choice for ...

...database, email, and display advertising campaigns. • Develop and monitor campaign budgets. • Plan and manage our social media platforms. • Prepare accurate reports on our marketing campaign’s overall performance. • Coordinate with advertising and media experts to improve marketing results. • Identify the latest trends and technologies affecting our industry. • Evaluate important metrics that affect our website traffic, service quotas, and target audience. • Work with your team to brainstorm new and innovative growth strategies. • Oversee and manage all contests, giveaways, and other digital projects. What are we looking for? We are searching for a highly-creative digital marketing manager to lead our marketing team. In...

...marketing database, email, and display advertising campaigns. • Develop and monitor campaign budgets. • Plan and manage our social media platforms. • Prepare accurate reports on our marketing campaign’s overall performance. • Coordinate with advertising and media experts to improve marketing results. • Identify the latest trends and technologies affecting our industry. • Evaluate important metrics that affect our website traffic, service quotas, and target audience. • Work with your team to brainstorm new and innovative growth strategies. • Oversee and manage all contests, giveaways, and other digital projects. What are we looking for? We are searching for a highly-creative digital marketing manager to lead our marketing team. In t...

...database, email, and display advertising campaigns. • Develop and monitor campaign budgets. • Plan and manage our social media platforms. • Prepare accurate reports on our marketing campaign’s overall performance. • Coordinate with advertising and media experts to improve marketing results. • Identify the latest trends and technologies affecting our industry. • Evaluate important metrics that affect our website traffic, service quotas, and target audience. • Work with your team to brainstorm new and innovative growth strategies. • Oversee and manage all contests, giveaways, and other digital projects. What are we looking for? We are searching for a highly-creative digital marketing manager to lead our marketing team. In...

...skin 2. brightening the eyes 3. sliming the the face a little 4. whitening teeth I am more interested in seeing the process rather than the finished result. I do not want to see: 1. YOU'RE WHOLE SCREEN - JUST GIVE ME THE PICTURE BEING EDITED. 2. NO DROP DOWN MENU'S WITH TEXT GETTING IN THE WAY. KEEP FOCUSED ON PROCESS. 3. YOU CAN PLAY WITH FILTERS / COLOURS ETC - BUT I ONLY WANT TO SEE THE AFFECT - NOT THE MENU - SO THIS LIKELY MEANS YOU JUST NEED TO RECORD A PORTION OF YOUR SCREEN. 4. Not really looking for time lapse - but speed up. Eventually this will be used to form the opening credits of a creepy horror film - so it should feel a little stalker like as that's the theme. I will need the screen recordings in as high a quality as possible. Minimum 10...

What is Hamlet's tragic flaw and how does it affect the play? i need 200words

Hi Just a quick fix on Prestashop 1.6. The before-price is missing in Grid View but does show overview - check the attached where you see the two different views (check where the cursor is to spot the missing before-price on one of the images). So as mentioned just a quick fix on a custom template. Its urgent.

Hey I'm trying to make a rust script coded in java because that's the language I'm familiar with and I need just a simple recoil pattern put into code. The code needs to control the recoil while still being able to move the cursor around as to look around in game. I have all of the x , and y coordinates that it needs to follow. The delay between every shot should be 130 Milliseconds. This is only one script to control one guns recoil. The recoil script should execute when I press left and right mouse buttons. I am learning java and this would be very helpful to me. Thanks!

5 page paper in APA 7th edition format, on the research question I selected. Be sure and follow the guideline for writing a research proposal. We have to use 5 sources for the paper. Research question: How do the 5-factor model of personality affect college I need to choose one of them student? but you can change the question but it have to be talking about the personality

Selection of a historical figure with adequate information written about them who you would really like to understand more 2) Approximately 10 pages long 3) 1/3 of the paper should describe the historical figure 4) 1/3 of the paper should summarize the personality theory chosen (ex. Principles of Adlerian theory, Freudian theory, trait theory. etc…) 5) 1/3 of...3) 1/3 of the paper should describe the historical figure 4) 1/3 of the paper should summarize the personality theory chosen (ex. Principles of Adlerian theory, Freudian theory, trait theory. etc…) 5) 1/3 of the paper should be applying the theory to the historical figure 4) Grammar counts. If I can’t understand your points because I am distracted by poor grammar, this wil...

...contain solutions for tablet (width 768px), mobile (width 360px) and desktop (width>=1920). Current page is build with Hugo (static site generator). Layout is based on Bootstrap 4. We do not need 100% support for IE 10 and above, but it should not look broken on IE. We can implement any html/js/css code you provide. Avoid using any other (large) frameworks or js libraries. Your change should not affect any existing perfomance KPIs much (e.g. Lighthouse). Desired improvements: - Feel mainly inspired by main page (I really like/love layout and position of items) - Feel free to provide a new (blue?) background (should match the rest of the page) - Salfeld hero with boy should be larger on desktop than on the current live page - Salfeld hero with boy should be below the text o...

Only Magento2 experts should compete for this project. Wants to have the magento “buyers cancellation module” to install in a eCommerce site. It is in Magento 2. To show that this module works with all Features. Needs to show proof before hand over. Also to train my employee to fix the common issues. Also to provide at least six months post-delivery support in regards to this or if it affect other parts of the system. To have the Magento “module for OTP” to install in my existing magento 2 eCommerce site. Requires Six months post-delivery support. OTP needs to be install for buyers registration, seller registration and admin registration. As well as with the job search client.( one of the function of the eCommerce site).

Hello, We use a custom advance search extension in our website instead of the default Magento search. We are looking to integrate this extension with the same functionalities to our flutter based mobile app. However, in order to use the...integrate this extension with the same functionalities to our flutter based mobile app. However, in order to use the extension on our mobile app, we need an API to be created. API should be create according to the following; -Based on Magento quality standards, we require the customization to be delivered in the form of a separate additional module (add-on). -Ensure that the solution will not affect any of our current extensions and their updates will not erase the custom solution. Please do let me know if there is any other questions Than...

I have a 1 min video of screenrecord. I have background music. I have logo and some text. You need to simply add music and in the end transition video to our logo. As it's screen record, you need to zoom in some places what cursor is doing. and probably cut some parts of video. I will tell you where and all. Budget 500 INR. This is just <1hr job.

...did the legal system support slavery, and how did the case of Celia challenge this system? Finally, how did slavery contribute to the divide that was growing in the United States by the mid-19th century? Then, look up a contemporary news article regarding race in America. Explain how race continues to play a role in American society. Do you believe that America's history of slavery continues to affect racial relations to this day? How has your experience in America been affected by America’s history of slavery and racism?...

A area chart showing weather data of 9 day. Each day contain 4 items > total 36 items. When first loading the page, the chart will show the first...data of 9 day. Each day contain 4 items > total 36 items. When first loading the page, the chart will show the first four items and allow to horizontal to the end. When scroll to the next day, the dropdown menu above (Today) will update Today / second day/ Third day. Please random show local file (below three icon) on second row of x-axis The page need to be responsive as the window width will affect the fontsize of text The page will show on a mobile app as we dont want to see the scroll bar on chart. But the chart has to support horizontal scroll function

1. Loss of contractility of muscle tissue would affect the function of an organ. Discuss the statement using an example for any 2 types of muscle tissue stated below: A. Skeletal muscle B. Smooth muscle C. Cardiac muscle 2. “Pancreas and liver are the two main organs that work together to ensure that the blood glucose level is maintained within a narrow range. If it is not maintained, diseases may occur.” A. Explain the physiological links between the 2 organs. B. Discuss how the physiology of the 2 organs differs and changes in type 1 and type 2 diabetes. 3. Select one pathological condition that can be studied in ancient skeletal remains. Explain how the study of that condition can provide useful information about the activities/lifestyle of past populati...

...would be seen on the landing screen along with the options to choose sessions from a whole list of categories. Once the buyer chooses a category, all the service providers offering services within the category (say Yoga) would appear on the screen along with their images, a brief write up next to their images, their average score and the price they charge per session. When the buyer browses the cursor over the image of the seller, he can also see the calendar (slots that are open along with timelines for the next week). If you click on the seller's profile, you would see a 30 sec video about the seller, link to his/her websites, instagram page etc. along with a small 100 word write up and the comments from previous users. Once the buyer makes the payment, they can book the...

We need an interactive price bar. The input is one number (the number of monthly deliveries), that the user can change by moving a cursor in a bar from left to right with the mouse. The output is a list of numbers (the delivery prices). An excel table maps the relationship between each input number and the corresponding output list of prices. See the attached file for more information

...Stage. Two at 9.6 km/hr. And consequently eight at the 10.4 km/hr. Stage. Oxygen consumption during walking was curvilinear instead of the earlier projected linear. During jogging, however, the oxygen consumption was linear when plotted. Energy consumption was found out to remain relatively constant when oxygen consumption increased linearly. Jogging speed did not affect energy consumption; on the contrary, walking speed did affect energy consumption. Heart and respiratory rates were higher in walking than jogging. "Subjects subjectively rated their exertion during walking significantly greater as compared to jogging across the range of overlapping routine speeds" (Greiwe and Kohrt 29). There was a significant increase in plasma lactate concentrations with the ...

...machine we want. So we do not need to go into code and backend of new machine and change the code. New plugin must be final and work without a need to change/add/delete any code. 2- logged-in user should be able to edit his design and his design and his changes must not affect other users’ design. Each user independently should be able to change, modify, save draft his design without affecting other users and their design. Each user will have separate design and independent and different design. users should not be able to affect each other’s work and each user’s design is completely separate and independent from other users. 3- All data must be recorded in standard way in WordPress database for each user. Each user must have separate data fields with...

...and ground floor parking. The buildings are made of twelve stories each of top of the two parking levels. We are looking for a very attractive yet cost effective design. The entries are supposed to be submitted for front elevation, side elevation, etc. Note that the building is symmetrical, both front & back. The main structure of the building is not to be changed but minor changes that do not affect structure might be introduced. The design suggested in the attached drawings are to be ignored. Winning entry will be expected to give more renders as deemed necessary by entrant and holder of contest. As we understand the time input required, this competition will be rewarded as follows: Winning Entry: USD 110 Second position : USD 40 The advertised price is for First pos...

approximately 3-4 page, double spaced essay. with at least 2 sources. all research and sources need to cited according to MLA style. part 1: discuss the general background of this issue: what is it? who is affected, what groups and indicidulas? how is it different in different cultures? part 2: discuss this issue in relation. to business: how does diversity affect business communication? what are some cultural barriers to communication? what are the challenges from a global perspective? part 3: discuss your own personal examples ( things you've seen or encountered) related to this issue of diversity.

Analysis of Kimpton Seafire direct and indirect competition(cayman islands)? Questions that I came up with: .) In your opinion what Hotel chains do you believe are in competition with the Kimpton Seafire? 2.) What factors give Kimpton Seafire advantage over its competition? (special attractions) 3.) What is Kimpton's position on the global demand for lower rat...opinion what Hotel chains do you believe are in competition with the Kimpton Seafire? 2.) What factors give Kimpton Seafire advantage over its competition? (special attractions) 3.) What is Kimpton's position on the global demand for lower rates? and how will the indirect competitors such as expedia and airbnb impact how well luxury hotels keep afloat when borders open? Do you feel that this will affect Kimpt...

...Room bill will be calculated per days. Doctor bill will be calculated as per doctor treatment, and medicine bill will be generated from medical store. Room Shifting In some cases patient wants to change their room. In critical condition we admit patient in I.C.U. After cure or stable condition we shift patient to general room from I.C.U. as per patient budget and wish. Patient room type directly affect their bill. Payment Bill After admit patient, hospital staff generates patient bill as per their treatment. We make payment entry when we receive payment from patient side. Discharge Patient When patient conditions well and pay full bill. Then we discharge patient from hospital. Manage Reports Reports are very important part of any system. We generate all reports as per hospita...

I need an editorial written in French. It can be about any subject (preferably something that will affect social status discussion), I just need it to be professional and given back to me before Tuesday night. Thank you.

...machine we want. So we do not need to go into code and backend of new machine and change the code. New plugin must be final and work without a need to change/add/delete any code. 2- logged-in user should be able to edit his design and his design and his changes must not affect other users’ design. Each user independently should be able to change, modify, save draft his design without affecting other users and their design. Each user will have separate design and independent and different design. users should not be able to affect each other’s work and each user’s design is completely separate and independent from other users. 3- All data must be recorded in standard way in WordPress database for each user. Each user must have separate data fields with...

...page is going to woocommerce page it should go to the booking appointment page. After login we need to redirect to booking page We need create the seperate schedule and booking slot time for each service. Example: ⦁ User want to book Bowling machine B on OCT 21 9am to 10am but it's showing red color ⦁ becuase some one booked bowling machine A on OCT 21 9am to 10am but why bowling machine B affect in the time slot ⦁ If we check all the service slots are booked on that particular time that we need to check for the all the service. ⦁ So any user can book the timeslot in any other different service with the same time. ⦁ But user cannot able to book the same service, same date and time that we have to check it again. 1.2 Removed Gender name 1.3 Change text DD--MM to MM...

tring tpromote mysekf, I am a reiki master and energy recontructionist. I pull out blockages in teh enrgy field that affect someone emotionally and physiclaly. I am also a channel/medium/psychic. I am also a speech language pathologist with ove3r 30 years experience. Not sure if the speech should be part of the healing website.

- How has consumer confidence changed during the pandemic, and how have these changes affected the banking sector? - How have consumer payment methods and banking preferences changed as a result of the pandemic, and how may these changes affect banks? - How have financial assistance payments to households (e.g., direct payments and unemployment enhancements) affected banks? Please try to contribute a couple of paragraphs related to the above issues and possible data/graphs

I am tryin...of data overlaid with 2 separate Y axis in a line chart. Both are time series data, one of the series has less data points than the other but the date ranges match. In the files section there is an example of this created in Python Highcharts. I need the graph to update once a day as a new CSV file is uploaded to the server daily. I would like the chart to show more detailed information if the cursor is hovered over a data point eg the exact date and value. Not particularly fussed what package is used to achieve this but free/open source would be preferred. Website hasn't been created yet, I want to be provided with all the code to achieve this so I can finish the site myself - though if I am happy with the results, I may contract the website to the person who help...

...communicate information, but they also affect our emotions and interpretation of the events, the characters, and the situations. These elements include: setting, music, sound effects, clothing, makeup, hairstyle, props, camera angles, lighting and shadows, and black and white vs. color film stock. In light of Wilmington's idea's compose a well- developed, well- organized essay in which you discuss the various elements of the mise en scene and there importance in telling the story, developing the characters and revealing the themes of The Third Man. To approach this essay, choose two specific scenes and discuss them separately in detail. Describe the scenes and point out how specific elements of the mise en scene convey important information and affect the emotion...

I would like to design a life preservation device for cattle specifically for natural disasters such as flooding. 500,000 cattle dies in the 2019 QLD floods. Not only did that affect the farmers but also the meat market and dairy market.

...whatever variable names you typically use and I'll just replace with our information.) Thanks index page contains *Search Box *After Search, Display of information can be above, or below, the search box. *Option to trigger camera as a barcode scanner, or be able to type numbers into the search box. *Cursor needs to be autofocused in Search box and when barcode scanner reads an ID Number, it then submits the search form, displays the information in a table, and clears the search box and places the cursor in it so we can scan the next barcode without touching keyboard or tapping into the search box. *Need a way to upload a CSV file to the database and can be a separate page, or at bottom of first page. Database that has the following fields. Employee ID , First Name,...

...the Address & Facebook URL fields from the Staff profile & Add Staff areas - be able to right-click on the items in the Action menus to use the standard right-click menu - prevent spaces from appearing at the beginning of the Unit names (see pic) - make the discussion area larger, so that you can see almost all parts of the message - change the order of the profile fields, & change how the mouse cursor proceeds to the next field - add an Address 2 field in Teameyo for the Clients - make phone number field conform to US template: (xxx) xxx-xxxx We are not newbies; we expect competence at all times; if we have to explain simple things to you, you will be eliminated very quickly. Also, please don't do the chit chat thing where you post messages that say "Hi&q...

1. Locate an article on ONE of the two below topics (the articles should be from a reputable site……NO WIKIs): How are language and thought related? Or How does Infant-Directed Speech affect children’s language development? 2. Write an annotated bibliography for the article you chose (Refer to the Annotated Bibliography example). An Annotated Bibliography is NOT a research paper. To write an annotated bibliography, you Cite the source (your article) on the first line of the page according to APA. Double-space the source and the body of your annotated bibliography. Type an overview of what a reader would find in the article you chose. Summarize the article. This is usually about five or six sentences. 3. The annotated Bibliography must be formatted a...

...accessible to consumers on its website or app. Users can arrange lodging, primarily homestays, and tourism experiences or list their spare rooms, properties, or part of it for rental. However, there is no certain way in which a host can decide the price for their listing. After analyzing the data from the Boston AirBnB, a model is built that can predict the price of a listing based on the features that affect the price of the listings. This model will be helpful for the hosts on AirBnB as they can put the right price for their listing, rather than depending on the neighboring prices. Data to use : We will be using the file which contains 3586 rows and 95 columns. Listings dataset has various features/columns such as neighborhood, property type, bedrooms

...3) Provide cross sections from Right of Way of adjacent property at "ALL" property lines paying particular to grade differential from proposed site to existing adjacent properties. Also show existing grades of at least 10' onto adjacent properties with sufficient "SPOT ELEVATIONS" to determine sites historic drainage pattern. Please provide swales at all property lines to avoid runoff that will affect the adjacent property owner. 4) Provide Pollution Prevention Plan per LDR 4.6.17 indicating location of silt fence and all other environmental control devices needed on a separate site and/or civil page of the same size. Please use City Details D 8.1 thru D 9.1c which can be found on the City of Delray Beach website located at: blic-

Applying a private school for grade1 kid, but as non-english speaker parent, it is a challenge. Please help on answering self/kid-introduction part. Maximum 4000 characters for each question. Writers nee...parent, it is a challenge. Please help on answering self/kid-introduction part. Maximum 4000 characters for each question. Writers need to do some research on the school we are applying. It is a super important section. 1. Why do you think TVT would be a good fit for your child? 2. Tell us about your child. 3. What are her strengths and weaknesses? 4. Describe any current circumstances that may affect your child’s performance in school? 5. Do you believe your child will need academic support to be successful at TVT? 6. Please tell us how you are active at your child’...

Acne vulgaris also known as acne is a common skin disease that is estimated to affect approximately 85% of the population at some point in their lives (Gold, Dhawan et al. 2019). It involves multiple pathological features including follicular hyperkeratinisation, increased sebum production, Propionibacterium acnes proliferation and inflammation. It is characterized by papules, open and closed comedones, pustules and sometimes cysts and nodules. Acne vulgaris is associated with self‐consciousness, depression, anxiety, insecurity in appearance and overall impaired quality of life (Bhate and Williams 2013). Conventional topical agents used in the management of acne, due to their irritation have tolerability problems leading to patient incompliance (Leyden 1998). Adapalene is a new 3rd...

The DAO development is using the qortal blockchain as the primary and base for its blockchain activities and hence, the DAO will inherits all primary features of the qortal core and this must be sustained in the DAO protocol without any major changes that will affect the smooth update of the core of the qortal blockchain during this genesis phase of the DAO protocol development. The DAO is hybrid of the Maker and SNX open-source projects and blended with some features of the Bisq DAO open-source. The primary blockchain of the DAO project is minting using Qortal core and other secondary minting as plugins, e.g., Waves staking blockchain wallet and SIPchain. However, the initial development phase now is more of Javascript for its UI/UX.

...possible (costly exercise we TRY and avoid) Some guiding thoughts are below; - Carry the wooden / timber theme throughout (where possible) - Statement Bedhead/Wall area - White bright walls - Colour where possible to assist standing out online ( etc) - Haven't been able to successfully use Neon lighting yet, but open to it if you see fit. - Open to rendering walls, wood paneling for affect - Indoor plants and trinkets needed - Coloured Bed Cushion/ bed runner One Bedroom - Install kitchenette on the designated wall only (services run here only water and power). More details below - Queen Bed - 42" TV wall mounted - Small desk / eating table (if we cant upcycle the existing ones well enough) - MAYBE items like; couch, armchchair, floor lamps etc to be used where apporp...

We have a code written for AutoHotKey that lets a user scan a barcode to open a print file, then the user scans it again to send to the printer, closes the print file, clears the field and puts the cursor back for the next scan. I need AutoHotKey to Scan Barcode, send the file to the printer after a few seconds, then close that print file after 20 seconds, and clear the data for the next scan. I attached the code and a video of it currently and how we use it. The sure should just have to scan the barcode once. Or if a barcode is manually entered it follows the same process.

...page is going to woocommerce page it should go to the booking appointment page. After login we need to redirect to booking page 2 We need create the seperate schedule and booking slot time for each service. Example: ⦁ User want to book Bowling machine B on OCT 21 9am to 10am but it's showing red color ⦁ because some one booked bowling machine A on OCT 21 9am to 10am but why bowling machine B affect in the time slot ⦁ If we check all the service slots are booked on that particular time that we need to check for the all the service. ⦁ So any user can book the timeslot in any other different service with the same time. ⦁ But user cannot able to book the same service, same date and time that we have to check it again. 1.2 Removed Gender name 1.3 Change text DD--MM to MM...

I published a short, heavily illustrated ebook on Apple Books entitled: A Quick Look at Organic Molecules: And How They Affect Climate Change, for beginners or anyone--young readers through adult--with limited or no training in organic chemistry. I need someone to review the book and post that review in the Apple Books Store online.