Hello!
I can already imagine this being full of anecdotes from life with little quips or moments of depreciation. For example, (a real life situation I've had, PG example):
"So a bit of background on my little sister. She has a genetic condition where her shoulders are constantly popping out of the socket. So now she has a medical reason not to do anything except being a bossy little brat. (Pause for laughs)
Back in high school, we used to hang out in the library- no we weren't nerds, we were just smarter than everyone else. One day my sister and I playfully bickering and she says to me "What do you have that I don't have?"
My response? Two functioning arms.
Our Librarian, a dear friend of ours, hits me on the back of the head. She then proceeds to ask my laughing sister if she feels safe at home with complete sincerity. Here's the thing, I love my little sister. We never argued over boys or clothes because I didn't like clothes and she doesn't like anyone. I love her even when I want to kill her! That's what it's like having a brother or sister! One minute you're ready to strangle them with their shoe laces, the next you're singing duets in the living room into hair brushes."
I'm not sure how close this is to what you'd want, but I'd love a crack at it!